Cure a yeast infection – with just yogurt!

February 13th, 2013

Stuff you’ll need:
-organic, sugar-free, plain yogurt cup(s)
-organic, cotton tampon(s) (without applicator)

Directions
Place the tampon in the yogurt cup, string-end up (see photo). If your tampon has an applicator, remove it so you’re only working with the cotton portion. Leave the tampon in the yogurt to soak for 10-15 minutes — it should be at least twice it’s original size when you remove it. Insert the tampon into your vagina, as you would normally when getting your period. Leave it in no longer than 8 hours.

Repeat this process until you feel relief and see a normalization in your vaginal discharge, and then continue it for another 24 hours to ensure you’re killing off lingering excess candida. The number of days necessary will depend on the intensity of your infection. Yogurt is pretty benign, and nothing I have researched indicates that one could “overdose” or create an undesirable imbalance by prolonging treatment. I haven’t had a serious infection in years – but these days if I start feeling a lil itchy, I’ll do this and just once overnight is enough. I prefer to approach feminine health as a perpetual awareness and management of one’s flora & fauna, rather than “OH NO I have contracted an infection, I must ERADICATE it and then I can STOP THINKING about my nether-regions.”

If it doesn’t bug you to eat a yogurt cup that’s just had a clean tampon in it, do so. Why waste it? Your body can use that additional acidophilus when consumed orally!

Prevention
Stop consuming sugar. Just stop. Next time you eat a candy-bar, see how your honeypot feels the next day. Kind of itchy, right?

Stop taking the pill. Now I was on the pill for years and never had this problem — but I have personal acquaintances that suffered for YEARS with chronic yeast infections because of it.

Eliminate white flour & fermented foods from your diet. Here’s a list from wikipedia.

Wear natural fibers, loose-fitting clothes. Or heck, just go naked or without underwear. Air is like the best remedy for everything. Unless you’re on fire.

Purified Neem (Azadirachta indica) Seed Extracts (Praneem) Abrogate Pregnancy in Primates

January 6th, 2013
Download PDF
Sutapa Mukherjee, * N.K. Lohiya, † Rahul Pal,‡ M.G. Sharma,‡ and G.P. Talwar*
*International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi-110067, India. †Department of Zoology, University of Rajasthan, Jaipur-302004, India, and ‡National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi-110067, India Name and address for correspondence: Dr. G. P. Talwar, Professor of Eminence, International Center for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi-10067, India. Fax: 91-11-6862316 Sumitted for publication February 13, 1996 Revised March 5, 1996 Accepted for publication March 5, 1996
The use of neem (Azadirachta indica) seed extracts (Praneem) given orally for abrogation of pregnancy in subhuman primates is described. Oral administration of Praneem was initiated after confirmation of pregnancy using Leydig cell bioassay estimating rising levels of chorionic gonadotropin (CG) in the blood from day 25 onwards of the cycle and continued for six days. Termination of pregnancy was observed with the appearance of blood in the vaginal smears and decline in CG and progesterone. Pregnancy continued in the control animals treated with peanut oil at the same dose. The effect was observed in both baboons and bonnet monkeys. The treatment was well tolerated; blood chemistry and liver function tests had normal values. The animals regained their normal cyclicity in the cycles subsequent to Praneem treatment. CONTRACEPTION 1996;53:375-378

KEY WORDS: Azadirachta indica, fertility studies, primates, pregnancy termination

Introduction
Over fifty million abortions are carried out each year around the globe. There is continuing need to develop additional methods, administrable preferably by oral route, to enable the termination of an unwanted pregnancy. A major step in this direction occurred with the introduction of RU486, a progesterone receptor blocking steroid which in combination with prostaglandins could bring about abortions in 96% of cases.1 Plant products have been employed for pregnancy interruption in traditional medicine in many countries. However, objective scientific studies on their efficacy and safety are lacking. We reported recently the abrogation of pregnancy in rats following oral administration of neem (Azadirachta indica) seed extracts;2 the treatment was effective in 100% of animals tested. The treatment was well tolerated and the animals regained fertility in subsequent cycles. The chemical composition of these extracts has been mostly delineated and these contain a number of chemically defined terpenoids and limonoids, besides fats and fatty acids.3 Although common mechanisms exist in reproduction of rodents and primates, there are also distinct differences. As, for example, the pituitary hormones continue to act as gonadotropins in rodents and no gonadotropin of chorionic origin is made in the species; whereas the pituitary is silent in primates and gonadotropic stimulus is provided by chorionic gonadotropin of trophoblastic origin. In order to gauge the potential application of the neem extracts as abortifacients, it was considered appropriate to test their action in subhuman primates. This article describes the results obtained in baboons (Pupio anubis) and bonnet monkeys (Macaca radiata).

Material and Methods
Praneem
Purified neem seed extracts (Praneem) were prepared from taxonomically characterized neem seeds. The oil was extracted in a table-top electrically driven machine (Komet oil expeller, IBG Monforts, Germany), followed by a two-step refining procedure by which the suspended materials were removed. The oil was kept at room temperature (25°C) overnight, the supernatant was decanted and centrifuged at 1500 g for one hour, followed by ultracentrifugation at 65,300 g for another 1hr. The pellet was discarded and the supernatant frozen at 4°C for further study. The preparation was screened to be free of aflatoxins B1, B2, G1, and G2 by TLC analysis on precoated Silica gel G plates using chloroform:isoamyl:alcohol:methanol (90:32:3) as solvent system. Pure aflatoxins from a kit (Sigma Chemical Company) were used as reference standards. The specifications of a batch (PVOO6) of Praneem were: specific gravity 0.905 g/ml; pH 5.7; saponificiation value 206.7; acid value <24; iodine value 24. The free fatty acid composition of the preparation as determined by gas chromatographic analysis was as follows: palmitic acid (19.6%); stearic acid (17.2%); oleic acid (41.2%); linoleic acid (0.82%); and other undetected minor acids (1.65%). The bitter principles include proto-meliacins, meliacins, limonoids, pentanortriterpenoids and norterpenoidal constituents as reported elsewhere.4

Animals
The study was conducted in two primate species, the adult baboons (Papio anubis) and bonnet monkeys (Macaca radiata). They were maintained in semi-natural conditions in the Primate Research Facility of the National Institute of Immunology. Animals of re- productive age only were employed for the study.

Fertility Studies
Female baboons were mated repeatedly with males of proven fertility during the estrous phase indicated by perineal sex swelling. For female bonnets, matings were set from day 8 to day 13 of the cycle.

Sample Collection for Estimation of Chorionic Gonadotropin (CG) and Progesterone Measurement Blood samples were collected on alternate days from day 25 of the cycle for measuring CG by bioassay and twice weekly for measuring progesterone by RIA. Each time, 2 ml of blood was drawn via the femoral vein; the serum was collected and stored at -20°C.

Bioassay for Estimating Chorionic Gonadotropin CG
Chorionic gonadotropin was estimated in the serum samples by Leydig cell bioassay as per method described by Van Damme et a1.5 The method’s basis is that short-term cultures of Leydig cells produce as- sayable quantities of testosterone in the presence of CG and the effect of the hormone is dose-dependent.

Radioimmunoassay for Progesterone
Progesterone levels in the sera samples were determined according to the method described by Brenner et a1.6 employing WHO matched reagents.

Treatment Regime
Neem seed extracts (Praneem) were given orally using a catheter tube after confirming pregnancy by measuring high levels of CG in blood. Animals were anesthetized with Ketamine (0.4 ml Ketamin hydrochloride, Themis Pharmaceutical Ltd, India) before treatment to avoid struggle and stress. Parallel controls received peanut oil.

Results
Pregnancy Termination
The study was conducted in five baboons (Papio anubis) and three bonnet monkeys (Macaca radiata). The pregnancy was monitored by appearance of CG bioactivity in the serum which normally increases over an eight-to-ten-day period before declining. The occurrence of conception was further confirmed by serum progesterone levels which in pregnant animals did not decline. After establishing that the animals were pregnant by these two criteria, they were administered purified neem seed extracts daily for six days by oral feeding tube. Three out of four baboons given the treatment experienced abrogation of pregnancy (Table 1). This was indicated not only by bleeding but also by both progesterone and CG levels falling to near zero levels (Figure 1). The baboon and monkey given an equal amount of peanut oil instead of Praneem continued to maintain pregnancy with sustained progesterone serum levels. Baboon 68, in which no termination of pregnancy took place following administration of purified neem seed extracts, had vomited the oil on the second day of the treatment. It is possible that this baboon did not receive an adequate dose of Praneem.
Figure 1 gives the data and kinetic changes in CG and progesterone profiles of the treated and the control baboons. The treatment was totally effective in the bonnet monkeys tested. The treatment was well tolerated except for one baboon where vomiting took place after the administration of Praneem on day 2 of the treatment. No other behavioral change or alteration in food intake was noted. Blood chemistry and liver function test parameters before and after treatment were not altered (Table 2).

Table 1. Abortifacient action of Praneem given orally in primates
Animal # Treatment
and Dose
Days of Treatment
Since LMP
Day of Onset of Bleeding and Its Duration (Days)
Pan 67
Pan 52
Pan 32
Pan 68*
Praneem
6 ml for 6 days
37-42
35-40
37-42
39-44
48-50 (3 days)
42-45 (4 days)
44-46 (3 days)
Pregnancy continued
Pan 63 Peanut oil
6 ml for 6 days
38-43 Pregnancy continued
MRA 526
MRA 672
Praneem
3 ml for 6 days
43-48
42-47
52-54 (3 days)
52-54 (3 days)
MRA 638 Peanut oil
3 ml for 6 days
36-41 Pregnancy continued
*Vomiting observed on day 2 of treatment.


Figure 1
Effect of administration of neem seed extracts (Praneem) given orally in pregnant baboons
Figure 1. Effect of administration of neem seed extracts (Praneem) given orally in pregnant baboons. Treatment given after confirming CG in blood as illustrated by (
). Termination of pregnancy observed by decline in CG (
) and progesterone; (
); (
) represents vaginal bleeding. Pan 63 shows the control baboon treated with peanut oil; Pan 68, the baboon where abrogation of pregnancy was not observed after Praneem treatment.

Reversibility
The reversibility of the effect of purified neem seed extract (Praneem) was manifested by the observation that baboons whose pregnancy was terminated by this treatment developed perineal sex swelling (due to estrogens) in the subsequent cycles. Normal cyclicity was regained after one irregular cycle. The animals mated with males of proven fertility. On becoming pregnant, the pregnancy proceeded to term. Pups born to these mothers (previously treated with Praneem) were normal. Figure 2 gives the case history of two such baboons. The treatment had no apparent residual effects on reproductive functions.

Effect of Praneem Oral Treatment on Progesterone
Data in Figure 1 show that soon after institution of the treatment with Praneem, progesterone decline commences. On the other hand, no consistent kinetic correlation is seen with CG levels. One could, thus, hypothesize that the treatment may be causing the lysis of the corpus luteum, the ovaries being the source of progesterone in these species at this stage of pregnancy. To test this hypothesis, normally cycling baboons were given oral treatment with Praneem for six days at the same dose from day 18 to 23 of the cycle. However, no shortening of the menstrual cycles was noted. Thus, Praneem does not appear to impair the corpus luteum function of the nonpregnant female baboon. The mechanism by which abrogation is caused may be similar to those identified during the previous study2 in rodents.

Discussion
This study demonstrates that Praneem administered orally for six days after confirming pregnancy by the rising levels of CG in the blood, brought about termination of pregnancy; peanut oil given by the same route at the same dose did not show this effect. The effect was reversible and fertility was regained in the cycles subsequent to Praneem treatment. The treatment was well tolerated with no residual effect compromising the future fertility of the animals.

Table 2. Hematological and clinical chemistry parameters as studied in baboons with Praneem
Praneem (n=3)
Parameter Before Treatment
(Mean + SEM)
After Treatment
(Mean + SEM)
Hb (g%) 11.7 + 0.26 11.6 + 0.1
TLC/mm3 (thousands) 7.3 + 0.44 7.0 + 0.26
DLC (%) Neutrophils 55.3 + 2.02 56.0 + 2.3
Lymphocytes 42.3 + 2.02 41.3 + 2.9
Moocytes 1.0 + 0.01 1.3 + 0.33
Eosinophils 1.3 + 0.33 1.3 + 0.33
Bilirubin (mg%) 0.43 + 0.03 .46 + 0.06
SGPT (IU/lit) 22.0 + 1.15 22.6 + 1.3
SGOT (IU/lit) 25.3 + 1.3 26.0 + 1.15
Urea (mg%) 27.3 + 0.33 29.0 + 0.01
Creatinine (mg%) 1.06 + 0.03 1.1 + 0.04
Glucose (mg%) 64.3 + 2.3 63.0 + 2.51
Total 7.1 + 0.2 7.23 + 0.14
Albumin 4.0 + 0.17 4.16 + 0.08
Globulin 3.1 + 0.033 3.13 + 0.06
n = number of baboons; TLC, total leucocyte count; DLC, differential leucocyte count; SGPT, serum glutamate oxaltate transaminase; SGPT, serum glutamate pyruvate transaminase.


Figure 2
Perineal sex swelling (***) pattern of baboons Pan 52 and Pan 67 and after treatment with Praneem in pregnant cycle. Both animals regained fertility in a subsequent cycle.
Figure 2. Perineal sex swelling (***) pattern of baboons Pan 52 and Pan 67 and after treatment with Praneem in pregnant cycle. Both animals regained fertility in a subsequent cycle.

Neem (Azadirachta induce) extracts have strong immunomodulatory properties.7 Evidence has been gathered to show that immunological mechanisms play a role in maintenance of pregnancy.8 Cytokines secreted by T-helper 1 cells, i.e., gamma interferon and TNF alpha, have detrimental effects on fetal survival, whereas cytokines IL-3 and GM-CSF help in gestation.9 Our previous work has shown that oral administration of purified neem seed extracts (Praneem) caused an elevation of both the immunoreactive and bioactive TNF alpha and gamma interferon in the sera. The draining mesenteric lymph node cells synthesized and secreted these cytokines and Th 1 type of cytokines were also present in the fetoplacental cultures. These transitory changes were presumably the basis of termination of pregnancy in rodents. Similar mechanisms may be responsible for termination of pregnancy in primates following ingestion of the neem seed extracts.

Acknowledgments
This work was supported by research grants of the Rockefeller Foundation and South-to-South collaboration in Reproductive Health. We would like to thank Dr. Om Singh and Dr. S. Majumdar for helpful suggestions.

References
1. Silvestre L, Dubois C, Renault M, Rezvani Y, Baulieu EE, Ulmann A. Voluntary interruption of pregnancy with mifepristone large-scale 645-8. (RU486) and a prostaglandin analog: A large-scale French experience. New Engl J Med 1990; 322: 645-8.

2. Mukherjee S, Talwar GP. Termination of pregnancy in rodents by oral administration of Praneem, a purified enema seed extract. Am J Reprod Immunol 1996; 35: 51-6.

3. Devkumar C, Sukh D. Chemistry. In: Randhawa NS, Parmar BS, eds. Neem Research and Development. India: Society of Pesticide Science, 1993: 63-97.

4. Siddiqui SS, Mahmood T, Siddiqui BS, Faizi S. Nonterpenoidal constituents from A. indica. Planta Medica 1988; 54: 457-62.

5. Van Damme MP, Robertson DN, Diczfalusy E. An improved in vitro bioassay method for measuring luteinizing hormone (LH) activity using cell preparations. Acta Endocrinol (kbh) 1974; 77: 655-71.

6. Brenner PF, Guerrero R, Cekan Z, Diczfalusy E. Radioimmunoassay method for sex steroids in human plasma. Steroids 1973; 22: 775.

7. Labadie RP, Van der Nat JM, Simons JM, Kroes BH. An ethanopharmacognistic approach to the search for immunomodulators of plant origin. Planta Medica 1989; 55: 339-48.

8. Wegmann TG, Lin H, Guilbert L, Mossmann TH. Bidirectional cytokines in the maternofetal relationship: successful allopregnancy is Th2 phenomenon. Immunology Today 1993; 14:353-8.

9. Chaouat G, Menu E, Clark DA, Dy M, Minkowski M, Wegmann TG. Control of fetal survival in CBA x DBA/2 mice by lymphokine therapy. J Reprod Fertil 1990; 89: 447-58.

RU486 (Mifeprex/Mifepristone): Buy the abortion pill from an offshore online pharmacy now, save yourself $500 later

November 9th, 2012
author’s note: this article has generated some informative discussion! The following have all been recommended as reliable websites delivering legit drugs.
aidaccess.org
alldaychemist.com
daynighthealthcare247.com
Prices and shipping times seem to vary a LOT and are subject to change – please read the comments to learn about others’ experiences with these companies. The websites listed above may be now more reliable than www.privatedrugstore.eu — some commentors have indicated that since I posted this (Nov 2012), reliability has decreased.]


Also check — this organization maintains a report card that rates sites for service and tests products for authenticity.

Nope, I’m not even kidding — www.privatedrugstore.eu has totally made my YEAR. The only downside is that I had to wait a MONTH for it to arrive, which had me on tenterhooks. Which is why I’m saying, stock up now, even if you aren’t pregnant, for every modern, empowered lady should have it in her medicine cabinet, for herself or a friend in need. The earlier you take it, the better, for you can achieve success with lower dosages and subsequently lesser side effects (google some mifeprex/misoprostol studies to see what I’m talking about) and the longer you wait, the statistically lower your chances of complete abortion become (which means you’d have to go to a clinic anyway to finish, if you only get it partially).

Doing things the “normal” way, and why I think it sucks
Now, the typical, recommended, approved, tested, documented blahblahblah method of chemical abortion in the United States is this: you go to a clinic, or your ob gyn, explain to them you’re pregnant and you don’t want a baby, and then they administer between 200mg – 600mg Mifeprex to block progesterone and “loosen” the uterine lining, then 800mg Misoprostol 12-72 hrs later to induce the contractions to get things “flowing” as it were. Then they bill you for $500. Or maybe you have to pay it upfront, depending on where you’re going. I have a FEW problems with this process:

1. Cost. WTF.
$500, are you NUTS? I’ve got a mortgage and a kid to take care of. I can only think of about a billion things I would much rather put that money towards. I don’t need financial stress on top of the crappy feeling that I screwed up and accidentally got pregnant. At the particular online pharmacy I bought from they even sell a combo package — you get the SAME thing that they administer at the clinics for $500, for $45. If you’re super broke, skip the Mifeprex, cuz you can even buy TWENTY 200mg Misoprostols for $27 (That’s 5 abortions). Ideally the regimen is started with Mifeprex, but I have managed to successfully terminate with a single Misoprostol when I caught it very early on, I think my period was about a week late at the time. If you’re super-early, one Mifeprex alone might work but it’s a bit riskier, because the thing you ultimately want is for the placenta to detach from the uterine wall, and if you’re more than just a couple weeks along, just blocking progesterone for a few days may not be enough – you need those contractions, which is what the Misoprostol does.

2. Privacy and simplicity, or lack there of.
I can go into a drugstore and take care of a yeast infection without explaining the gory details to anyone, why the heck can’t I do the same if I discover my period is late? I have no problem whatsoever with anyone terminating a pregnancy, but something I totally hate about American culture is either the feigned look of empathetic pity you get from people that have never been through it, or on the more extreme end I have heard of judgmental gynecologists insulting their patients’ lifestyle. Or yet worse, if you’re in a red state, you might not find a place to serve you at all.

3. Time.
I hold a full-time job at a technology firm, take care of my baby daughter, make time for my partner (her daddy), play 3 sports, and pursue my artwork on the side. And occasionally like to have a social life. Why should I have to schedule appointments at a providers convenience instead of just buying what I need over the counter or online? Not to mention, they usually make you wait until you’re 6 weeks along – so you get to be all stressed out about it for a while instead of taking care of it immediately.

4. Dosage.
This is an interesting one. After the time I took just one Misoprostol when a week late, I had come to the conclusion that they REALLY overdo it — that the 800 mg of Misoprostol was responsible for causing contractions so intense you feel like you’re giving BIRTH, and that the same could be accomplished with much less. However this time around, I’m led to believe it’s the Mifeprex + Misoprostol combo in the system that is responsible for vomiting, diarrhea and knee-buckling contractions. Even so, I think they over-prescribe the Mifeprex. One 200 mg Mifeprex is likely to make you a little dizzy, a little nauseous for a few days, but not enough to need to take time off work (for me anyway), and it’s enough to get you bleeding by day 2 or 3. I’ve read “official” recommendations that state 400-600 mg taken all at once. Ugh. I don’t know what that does, but I don’t imagine it’s pleasant.

My Recent Experience
So here’s the whole saga from start to finish. I’m going to mark it by LMP (Last Menstrual Period). So week 4 is when I was expecting my period. Week 5 is when I realized “oh shit, I’m a week late.”

Week 5 – 6
Having clearly miscalculated ovulation due to some post-baby irregularity and neglecting to take my usual herbal precautions due to being busy to an insane degree, I found myself a few days *late.* I got a test from the drugstore, and lo, there appeared the faint line confirming my worries. Crap. For a week I went with neem suppositories and ingesting massive amounts of Cotton Root bark, none of which, did a damn thing. That’s when I started looking around online and reading up on “illegal” pharmacies. I found one forum where commentators discussed online pharmacy ratings (I think stuff like pharmacyreviewer.com or pharmacychecker.com or something but I can’t remember), One person questioned the low rating of a pharmacy he had bought from numerous times with positive experiences. The discussion meandered into the “why” behind the low ratings, and some suggested that large “legitimate” pharmaceutical companies purposely do this to try to undermine competition from companies selling the same drugs for a fraction of the price. Huh. So I followed one commentators link to privatedrugstore.eu, found what I wanted, hesitated, pondered, worried I was going to be the victim of credit card fraud, or that it might not work, and a hundred other unpleasant scenarios, before I finally purchased 1 pill of Mifeprex. Why just one Mifeprex? Well, after one of my chemical abortions under the supervision of an RPA, I had started bleeding on day 3 after taking the initial Mifeprex, but before I had taken the Misoprostol. My hypothesis was that ALL I needed to do was block progesterone, and poof, the pregnancy would be weakened enough to leave my body without inducing contractions. So OK, I was wrong, so for chrissake, don’t do this.

Week 6 – 10
My order was placed, all I had to do was breath deeply and wait. This is easier said than done. Especially when the first trimester is making you tired and hungry but you’re keeping it to yourself instead of beaming and exclaiming to everyone that you’re pregnant while demanding their subway seat, or pork chop, or chocolate cake, etc. This can be lonely and stressful unless you have someone close to share it with. Week 10 – 13
So the Mifeprex finally arrives. Whew. I was able to track it online, but there was about a week delay due to extreme weather conditions affecting the post office. It came in a small padded envelope, there was a postage stamp from Singapore, and nothing on the outside indicating what it actually was. The pills were in a foil blister pack like the image at the beginning of this post. I swallowed it, and around 24 hours later, started to bleed. Hallelujah. However, it didn’t continue. By 48 hours after I had taken it, the bleeding had slowed and then stopped. I got online to see what this means in the context of a miscarriage and found out it’s medical definition is “threatened miscarriage,” that it happens with some frequency, and as long as the fetal heart-rate remains strong and the placenta is intact, the pregnancy will in all likelihood continue. *sigh.* So I did a little more research, because the Mifeprex is expensive, and I was starting to get worried that I had missed the window to terminate with a non-invasive method. I REALLY did not want to go into a clinic and have my insides vacuumed out. I found an inspiring medical abstract that encouraged me to place another order, this time for Misoprostol only – 20 x 200mg pills. Here’s the text below:

Multiple-dose vaginal Misoprostol and single-dose misoprostol plus oxytocin for termination of second-trimester pregnancy.

Zangeneh M, Malek-Khosravi S, Veisi F, Rezavand N, Rezaee M, Rajatee M.
Source: High Risk Pregnancy Research Center, Department of Obstetrics and Gynecology, Imam Reza Hospital, Kermanshah University of Medical Science, Kermanshah, Iran. mzangene.59710@yahoo.com

Abstract
OBJECTIVE:
To compare 2 different methods-multiple doses of misoprostol and a combination of misoprostol and oxytocin-for termination of pregnancy in the second trimester.

METHODS:
Between 2006 and 2008, 120 women undergoing termination of second-trimester pregnancy in 2 hospitals in Kermanshah, Iran, were enrolled in a randomized trial comparing 2 treatments. In each treatment group, an initial vaginal dose of 600 μg of misoprostol was placed in the posterior fornix. After 6 hours, an intravenous infusion of concentrated oxytocin was given to women in group A, and 400 μg of vaginal misoprostol was given every 6 hours to women group B, up to a maximum of 4 doses. The outcomes were compared via χ(2) and independent t tests.

RESULTS:
Within 30 hours, 96.7% of women in group A and 96.7% of women in group B delivered successfully. The average duration between induction and delivery time was 12.3±6.0 hours in group A and 12.1±6.0 hours in group B (P>0.05).

CONCLUSION:
The use of misoprostol with oxytocin, and multiple doses of misoprostol gave similar results for termination of pregnancy in the second trimester.

Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
PMID: 22261129 [PubMed – indexed for MEDLINE]

Week 13
So this time it only took 2 weeks to arrive. From what I read from the forums on offshore pharmacies, is a little more normal than one month. By this time I was starting to gain a little weight and my breasts were getting bigger. This is no fun – I urge you not to wait so long if you’re going to terminate, seriously.



Photo of what I received – labeled, dated blister packs. Regardless of where you order from, I think if it’s not sealed, accurately labeled and stamped with an expiration date, I probably wouldn’t trust it.

The night they arrived I decided I would take 2 pills (200mg each) vaginally before going to bed, instead of 4, as I had done under the supervision of medical professionals previously. Why? I was afraid of the pain and vomiting and diarrhea I had experienced when doing things the proper, clinic-approved way, with Mifeprex followed by 4x 200mg pills of Misoprostol; I thought this unpleasantry could be avoided with a lower dosage. It took about 3 hours before I felt pressure in my lower back, like a heavy period. I began to bleed. The next morning I awoke, was still bleeding, but hadn’t seen any evidence of a fetus or placenta, so I knew I was still pregnant. The bleeding continued, but subsided somewhat throughout the day. So the next night, I decided to do the same, with 3 pills inserted vaginally instead of 2. Again, similar results – after about 3 hours I had some lower back pressure, like a period, also accompanied by some minor chills but nothing crazy. I followed it up with 2 more pills, I’m not sure how many hours later, but I’m assuming around 4 since the chills had subsided and I was presumably past the ‘peak’ amount of medicine in my system. The following day I continued to bleed some, but again, the products of conception were not expelled. So the third night, I decided to do 4 pills. I felt some back pressure, bleeding, and at one point a few chills but nothing too intense. The next morning, I started feeling some very heavy cramping, not unlike labor pains. I breathed heavily and bent forward to ease myself through it. I was in the bathroom standing at the vanity when suddenly my pants became soaked in a clear fluid. My water had broken. I got onto the toilet, and a moment later everything came out – blood, lining, placenta, and a fetus about 4-5 cm long. I fished it out of the toilet to examine it and put it in a glass container. Later on I wrapped it in a flower bloom, said I was sorry, and buried it at the base of one of my plants. This is another reason I recommend not waiting so long to terminate — a well-developed fetus is not really something you want to look at, unless you are super relaxed and emotionally settled about this sort of stuff. Very early on, it’s a tiny blob, but it gets to look more and more like a little person the longer you wait. Nothing in the world could have outweighed my RELIEF that I was not going to have another baby, but all the same, it’s kind of icky, even if you’re a freak like me and totally fascinated by that shit.

Conclusions and recommendations
This experience taught me a few really important things, which I will pass on here. I’d also like to point out that I have no medical certification of any kind, and according to most rational people, have absolutely no business giving out medical advice. Now that that’s out of the way:

1. There DO exist offshore, illegal pharmacies, selling legitimate drugs. How you decide to trust one, well, that’s tricky. I threw caution to the wind and just decided to trust that it would arrive, that I wouldn’t be overcharged or have my identity stolen, that it was the correct drug within it’s expiration date, and that everything would be OK. Is this how all of them operate? I doubt it. All I can recommend is this one particular website I used – privatedrugstore, providing it is owned and operated by the same people that are doing it as I write this. I’ve included a screenshot of the site I bought from below for reference, in case it closes or the domain name gets bought by someone else.

privatedrugstore.eu screen capture

2. Expect 2-3 weeks for shipping, and longer if extreme weather conditions or other disasters delay the post office.

3. Mifeprex is not necessary at all. In fact, FUCK Mifeprex. Without the Mifeprex, you can rest assured the process will be pretty mild. Mifeprex alone is responsible for a bit of queasiness. Mifeprex & Misoprostol in the body together equals a couple of miserable hours doubled over in pain, vomiting up bile, and chills up and down your whole body even with 5 blankets on top of you. With Misoprostol alone, it’s like a heavy period; the most intense part will be the cramps a few hours or a day after you take the pills, when your cervix starts to open up to let the products of conception pass. This is the not fun part, so be sure not to be at work or school when it happens – do this stuff on a weekend. And if you’re trying to hide this from your parents or whomever, make sure you can get the bathroom to yourself.

*EDIT* July 2019 Ok so I wrote the above based on MY experience, but that’s not necessarily going to be YOUR experience. The efficacy rate for Misoprostol alone is 85%. The efficacy rate for the MTP kit is 95%. There is research on successful termination with Mifeprex alone, albeit limited, but it would appear that blocking progesterone alone for a few days can be a much gentler experience than inducing contractions. Side effects will vary. I think a prudent approach when ordering offshore is to order 1 Mifeprex and a dozen Misoprostol. Try out the Misoprostol alone, and you have a high chance of success. If it doesn’t work, then have another go, starting with the Mifeprex followed by the Misoprostol.

4. If you can afford it, order a little more than you think is necessary. Ordering just the Mifeprex and no Misoprostol, in retrospect, was a dumbass thing for me to do. And even with the Misoprostol, maybe because I was goofing around with dosage, or maybe because I was over 12 weeks along, I ended up using 11 pills in total. 4 x 200mg pills following a progesterone-blocker is generally recommended for up to 9 weeks LMP. So there’s a few factors to consider – it’s very hard to say in this case that it was specifically the 4 pills on the last night that resulted in success, OR if it was the multiple attempts across 3 nights that did it. When using herbs (for anything – a cold, a bacterial infection, whatever), slow and steady usually wins the race, e.g., you don’t generally take one dose and BAM, expect results, that’s a more recent phenomenon of modern medicine & technology. In any case, it’s comforting to know there’s extra if your first attempt doesn’t work. I also still have 9 pills in my drawer, for a rainy day.

5. Dosage… If I was to do it all over again, here’s how I would approach the important issue of DOSAGE: 4x 200mg pills vaginally of Misoprostol, each night upon going to bed, until the products of conception are expelled. This is mainly for convenience — if you lead a busy life, night time is probably the only opportunity you have to be prostrate for several hours. I’ve also received the recommendation to do it early in the morning – set your alarm for 5:00 am, insert the pills, and things will get going by the time it’s just getting light out — which can be a much less scary time than the night to try something out when you don’t know precisely what the outcome will be.

*EDIT* July 2019 Since corresponding with so many women about their experiences, I’m changing my stance on this. These medicines affect every woman differently, and there IS NO one-size-fits-all approach. You might be successful with the MTP kit, with Misoprostol alone (2-12 200mg pills), or with Mifeprex alone (400-600mcg in 2-4 doses over a couple days). Or you might not — you might have to tinker a bit and take some of this and then some of that over the course of a few days. Hell, you can terminate successfully in one way, and do the same thing a year later, and the stuff DOESN’T feel/work the same! When I originally wrote this, I still believed it was preferable to terminate a pregnancy under the supervision of a healthcare professional, but not anymore. I believe each woman has to have the freedom to play around with the pills, listen to her body, and make adjustments accordingly, and this is the path to a 100% efficacy for medical abortion. Doctors are severely limited in what they prescribe. BTW, would you say the healthcare industry, including the doctors and researchers publishing papers, is a female-dominated industry? Nope. Buncha old sexist white dudes driving that wagon. So why are we asking them to tell us how our bodies work or for permission to figure it out? Blow me.

6. Open a new email account
to make your order, because once they have your email address, prepare to get SPAMMED with offers from other online pharmacies.

7. Schedule an appointment with an ob-gyn for a pelvic exam, after you believe all the products of conception have passed, to ensure the process has completed. If you experience heavy cramping after you believe everything has passed, you might have a uterine infection, and you should go to urgent care to be prescribed some antibiotics. Lie and say you had a miscarriage. Once you’ve been bleeding for a few days there won’t be any evidence of the stuff in your vagina or your system.

A few words on the whole damn subject
It seems to me that the FDA is making what COULD be an easy, private, inexpensive process, a royal pain in the neck. Why? Maybe to cover their butts from getting sued, in case you aren’t administered enough, and you have to go in for a surgical abortion if it doesn’t work. Either that, or its some Republican conspiracy to make pregnancy termination so incredibly unpleasant that you’re more likely to go through with the pregnancy, because god only knows, what this planet needs is more PEOPLE. I HAVE read that more than one key person has resigned from the FDA over the decision to stall Mifeprex’s over-the-counter availability – because they felt it was for political reasons and NOT grounded in health facts.

I think a common question this raises in most of our minds is “well, SHOULD it be so easy?” For many, the idea of a new life hangs in the balance, and some inner voice suggests it’s immoral for women to repeatedly seek abortions. To a woman that does not want a baby, I think the point of sperm meeting egg, or the point of a zygote implanting in the uterine wall holds little significance. I think many take desperate measures, when simple ones are not available. If there is zero detriment to the health of the woman in question, if it is inexpensive and doesn’t take her out of work — well… is it such a bad thing? I’ve read about Sylphium in ancient Cyrene, that physicians recommended it once a month for “preventing anything from forming, and eliminating anything that might be there.” Granted, ancient times were considerably more brutal than modern civilized ones, but in this one aspect – the lack of public scrutiny and controversy of women’s handling of their fertility, I cannot come up with a logical argument against it.

I know one day I may have to answer these questions for my daughter. And I know that it’s possible that one day, when she is a teenager, she’ll come home to tell me she’s pregnant and not ready to take the step of being a parent. If that happens, I want to be able to offer her an easy, simple, shameless and inexpensive solution. On the other hand, I don’t want to encourage her to go out having lots of unprotected sex, or to ignore holistic preventative birth control and the workings of her cycle because it’s just so easy to pop a pill. I want her to treat her body and temple with care and deliberation, and never to be at war with it, or at the mercy of it’s hormones or maladies, or to believe that it’s something to be controlled only with the help of big pharma.

Another important point of consideration, is the zero benefit + great detriment of unplanned pregnancies on the whole. I have seen instances in my own social circles, where slower child development *appeared* to correlate with mom not knowing that she was pregnant for the first few months. Like every mom, I watch my child’s development with care and concern. Even knowing from the moment her daddy and I decided to try and make a baby, even with taking all the precautions and supplements from the moment i thought she might be in my tummy, and pouring over countless books and forums about what I could do to help her growing little body and brain, I still worry. I still fret over details. I am relieved when I read that she’s on schedule with crawling, babbling, each new tooth that comes in and each new facial expression she gives me. Maybe it’s silly, but everyone with a kid knows what I’m talking about. It’s hard not to judge yourself, when you judge the progress of your little one.

This is not to say slower development is mom’s *fault*. It is the world we live in. Perhaps there was a time when not knowing one was pregnant for the first month or two had little impact on the health of the child eventually born. But these days, what with mass-produced food so lacking in nutritional value that one NEEDS supplements throughout pregnancy, what with lifestyles abounding with fast-food, alcohol and radiation, what with statistical evidence that fasting/dieting during the first critical months creates spikes in birth defects 9 months later, my opinion is that each pregnancy SHOULD be planned and nurtured. This doesn’t even touch on the implications of a social structure that leaves individuals with little to nothing in the way of social protections if they aren’t blessed with the luck of the marketplace. A woman knows when it’s a good time to have a baby, and when it’s not. And this is of greatest consequence to the ultimate health and happiness of our society, and planet.

Gripe water (tummy tamer for colicky babies)

March 24th, 2012

Ingredients
1/8 cup chamomile
1/8 cup fenugreek
1/8 cup anise
1/8 cup dill
1/8 cup fennel seeds
1/8 cup ginger

Directions
Steep equal parts of all ingredients in 4-6 cups boiling water for 15-20 minutes: Can be added to breastmilk hot or cold – I usually make a batch and bottle it to I can add as needed over the next few days; 2-3 tbsp mixed with 2-3 ounces of breastmilk once per day.

I came up with this tea based on some advice from herbalist friends and various web sources. My daughter was crying uncontrollably at night and nothing we did seemed to ease her clear discomfort. A little of this added to my breastmilk in a bottle seemed to do the trick (though babies change so rapidly and so uniquely, it’s nearly impossible to tell what you did right… unless I suppose you had identical twins for a control setup). After a 1 week I skipped for a couple days and she was back up crying. Since then we give it to her every day; it doesn’t seem to matter what time – it appears that as long as she has it once a day, it keeps her stomach calm through several feedings.

Science: Dymaxion Sleep

December 29th, 2011

Time Magazine: Monday, Oct. 11, 1943

Sleep is just a bad habit. So said Socrates and Samuel Johnson, and so for years has thought grey-haired Richard Buckminster Fuller, futurific inventor of the Dymaxion* house (TIME, Aug. 22, 1932), the Dymaxion car and the Dymaxion globe. Fuller made a deliberate attempt to break the sleep habit, with excellent results. Last week he announced his Dymaxion system of sleeping. Two hours of sleep a day, he said firmly, is plenty.

Fuller reasoned that man has a primary store of energy, quickly replenished, and a secondary reserve (second wind) that takes longer to restore. Therefore, he thought, a man should be able to cut his rest periods shorter by relaxing as soon as he has used up his primary energy. Fuller trained himself to take a nap at the first sign of fatigue (Le., when his attention to his work began to wander). These intervals came about every six hours; after a half-hour’s nap he was completely refreshed.

For two years Fuller thus averaged two hours of sleep in 24. Result: “The most vigorous and alert condition I have ever enjoyed.” Life-insurance doctors who examined him found him sound as a nut. Eventually he had to quit because his schedule conflicted with that of his business associates, who insisted on sleeping like other men. Now working for the Foreign Economic Administration, Buckminster Fuller finds Dymaxion working and sleeping out of the question. But he wishes the nation’s “key thinkers” could adopt his schedule; he is convinced it would shorten the war.

Intermittent sleeping was not originated by Fuller, has respectable scientific backing. Last week the Industrial Bulletin of Arthur D. Little, Inc., famed Cambridge, Mass, research firm, which published Fuller’s sleeping plan, noted a strong point in its favor: most sleep investigators agree that the first hours of sleep are the soundest. Some pro-Fuller evidence:

Photographs and electric devices to record movements show that the average sleeper, who changes position at least 40 times during an eight-hour stretch, is quietest in the first two hours, then grows progressively more restless.

At Colgate University sleep investigator Donald A. Laird found that people awakened after four hours’ sleep were just as alert, well-coordinated physically and resistant to fatigue as those who slept eight hours (but they did lose in accuracy and concentration).

* A Fuller word representing “dynamic” and “maximum service.”